1. By 2050 we may not be needing any input output devices like keyboard, mouse, touchscreen or touch pads. Your thoughts are enough to type, search or do any task on your computer which you normally do with your I/O devices. It also means that you will have to mask yourself with TTs or Thought Tress-passers who will try to steal your thought and try to read your mind without your permission and try to know your secrets. This will also lead to a new type of mind-hacking where hackers will try to gain access to your personal and financial details over the web with the help of some social hacking. Companies like google who search keywords from your emails to judge what ads might interest you, may start browsing your mind and see what you really need and what you really want. Future matchmaking will be much easier with automated softwares with access to your minds may find a proper match for your on your favorite matrimonial or dating site. The product you may want to watch out in this segment is NeuroSky Mindset with its future variations.
---more such nonsense for later... :P